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Hi
I am interested in using this package to calculate α using my SNP data (VCF files) for Drosophila. As far as I can tell, the input should be d0 and d and a file containing the DAF and polymorphism data (synonymous and nonsynonymous). However, I am not sure how exactly I should calculate the values for d0 and d. It is not clear what should I use as a neutral reference region.
In addition, I was looking at the provided example file (x,pN,pS) and I am not sure what each row is representing. Is each row a population, gene or maybe a region?
Not sure if this is still maintained but if someone see this, any clarification on the above would be much appreciated.
Thank you
Javier,
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